生命科学/ Life Science Products

蛋白组学产品: Proteomics for Life Science

我们的产品：质谱方法包；蛋白酶；糖苷酶;多肽脱盐和去丰度蛋白产品和技术是蛋白组学和生物制药的生命科学技术

Our products: proteomics kits; Endoproteinase, Glycosidase; Peptide Desalting kits and Protein Depletion kit is for Proteomics Research and Biophamaceutical study in Life Science.

蛋白酶: Endoproteinase for Proteomics

蛋白酶水解变性蛋白质变成多肽，只有多肽才能被色谱分离和质谱分析

我们的产品：蛋白酶-C系列， 蛋白酶-N系列产品，是蛋白质质谱测序新技术

专门纯化的质谱级的蛋白酶用于蛋白组学的研究和生物制药工程

产品特点：

• 不自残：适合蛋白组学生物标记物的应用，保证蛋白鉴定的专属性

• 高活性：活性高用于蛋白测序新技术化

• 质谱纯：超纯度，冻干粉产品
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Endoproteinase turn the proteins into peptides, then are separated by LC and detected by mass spetrometry for biological data analysis.

Our products:  Endoproteinase-C bond and Endoproteinase- N bond series products. these used for  the new protein sequenceing  technology.

specifically purfied to provide option digests for protemics application and Bio-pharmaceutical engineering .

the key feature of product:

• No self-hydrolysis: be best  for proteomics Biomarkers and ensure specificity of protein identification

• Activity: BEST for low abundance protein identification

• High purity: ultra purity, lyophilized for  proteomics research.

糖苷酶PNGase F: Glycosidase

抗体和抗体载体作为治疗药物。N-glycan Asn297 Fc区域的免疫球蛋白IgG功能Asn297的保留的N端寡糖是活性官能团

PNGase F是最有效的酶，可以酶切所有N端连接的蛋白寡糖。PNGase F消化酶切aspargine天冬氨酸片段后，剩下完整的稳定的低聚糖用于进一步分析研究

A number of antibodies and antibody fusions are currently used as therapeutic agents. A conserved N-glycan at Asn297 of the Fc region of IgG is critical for functional activity.

PNGase F is the most effective enzymatic method for removing almost all N-linked oligosaccharides from glycoproteins. PNGase F digestion deaminates the aspargine residue to aspartic acid, and leaves the oligosaccharide intact, keeping it suitable for further analysis.

质谱方法包－定性: Kits for Protein Identification

质谱方法包为复杂蛋白样品鉴定和研究提供简单的，可重复的解决方案，是蛋白组学研究的新思路，可以获得倍数量级的蛋白鉴定的数据。主要应用和技术特点：

• shotgun 混合蛋白鉴定

• 生物标志物的鉴定

• 磷酸化蛋白质鉴定

2D 色谱柱：

• Biphase 离子交换－C18色谱柱

• CTI 300A孔径填料技术

• 倍高上样量，超高分辨率和灵敏度

• 高重复性色谱技术

梯度洗脱液：10阶

• 专有有机酸碱洗脱液

• 避免了高浓度盐污染问题

• 无离子抑制效应

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This methods for each protein identification and study provides a simple solution can be repeated, is a innovation of proteomic research by mass spectrometer, and could got multiple level protein identification data each running. The application and key feature:

• The shotgun hybrid protein identification

• Biomarkers discovery

• PTM analysis

2D column:

• Biphase ion exchange and C18 chromatographic technology

• CTI 300A packing technology

• times sample loading, Ultra high resolution and sensitivity

• Highly repeatable chromatographic technique

         Gradient elution buffer: 10 order

• special Organic acid eluent

• Avoids ion suppression effect

• no high concentration salt pollution problems